Bin Xie's paper entitled Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody was published in PNAS on August 3rd 2022. Congratulations Bin!!!!

Link to paper

Link to press release describing our work

Andrew's and Ramesh's co-first author paper, entitled Cadherins can dimerize via asymmetric interactions was published in the July 22nd issue of FEBS Letters. A figure from their article was also chosen as the journal cover image. Congratulations Andrew and Ramesh!!!!

Link to paper

Our new Leica STELLARIS 5 microscope has been installed in Room 49 Kemper Hall. Capable of three color laser scanning confocal, phase contrast and DIC imaging.

We are very excited to do new science with it.........

Our R01 grant from the NIH to develop methods to study cell-cell adhesion has been successfully renewed. Congratulations to all the lab members.

Grant details on NIH RePORTER

News story describing our grant

Ramesh's and Andrew's co-first authored PNAS manuscript  Inside-out regulation of E-cadherin conformation and adhesion, has been recommended in Faculty Opinions as being of special significance in its field. Congratulations Ramesh and Andrew!!!

Link to the recommendation

 

Ramesh's and Andrew's co-first author paper, entitled Inside-out regulation of E-cadherin conformation and adhesion was published in the July 27th issue of PNAS. Congratulations Ramesh and Andrew!!!

Link to paper

Blog post on UC Davis egghead, describing our work

Ramesh and Andrew successfully defended their Ph.Ds. They did an awesome job. Congratulations Dr. Ramesh Koirala and Dr. Andrew Priest.

We have been awarded a new R01 grant from the NIH to study mechanosensitive cadherin adhesion and its regulation. Congratulations to all the lab members.

Grant details on NIH RePORTER

Link to a news story on our grant

Shafraz's and Bin's manuscript entitled Mapping transmembrane binding partners for E-cadherin ectodomains was published in the December 2020 issue of PNAS. Congratulations Shafraz and Bin!!!!

Link to the manuscript

Link to news story describing our work

Patrick's manuscript entitled Robust scan synchronized force-fluorescence imaging was published in the February 2021 issue of Ultramicroscopy. Congratulations Patrick!!!!

Link to the manuscript